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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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acsAacetyl-CoAsynthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)    
Predicted Functional Partners:
RN09_3014
2-oxoglutarate oxidoreductase subunit KorA.
  
 
 0.957
CitA
Citrate synthase 2; Belongs to the citrate synthase family.
  
 0.950
Pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.948
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.948
GltA2
Citrate synthase 1; Belongs to the citrate synthase family.
  
 0.946
GltA1
Methylcitrate synthase PrpC; Belongs to the citrate synthase family.
  
 0.946
GlcB
Malate synthase; Overlaps another CDS with the same product name.
  
 0.938
FadA3
Beta-ketoacyl CoA thiolase FadA; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.927
FadA2
acetyl-CoA acetyltransferase FadA; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.925
FadA
Acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.925
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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