Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_4491cAMP receptor protein. (224 aa)    
Predicted Functional Partners:
RN09_2754
Hypothetical protein.
  
     0.686
PknL
Serine/threonine-protein kinase PknL.
     
 0.661
Gap
Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
 
 0.631
RN09_4487
Hypothetical protein.
  
  
 0.619
RN09_2799
LysR family HTH-type transcriptional regulator.
   
 
 0.617
OxyS
Oxidative stress response regulatory protein OxyS; Belongs to the LysR transcriptional regulatory family.
   
 
 0.614
RN09_0465
HTH-type transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
   
 
 0.611
RN09_2444
HTH-type transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
   
 
 0.611
RN09_4486
Serine protease.
     
 0.608
RN09_4490
Membrane protein.
       0.591
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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