Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
whiB-6Transcriptional regulator WhiB4; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (100 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.773
RN09_3513
Hypothetical protein.
  
     0.739
RN09_2255
HTH-type transcriptional regulator.
  
   
 0.731
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 
 0.704
SecG
Protein-export membrane protein SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
 
     0.676
RN09_0643
Hypothetical protein.
  
     0.648
whiA
Transcriptional regulator WhiA; Involved in cell division and chromosome segregation.
  
  
 0.639
RN09_3916
Anti-sigma factor RshA.
 
 
 0.625
nucS
Endonuclease NucS; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
 
   
 0.614
RN09_3042
Hypothetical protein.
  
     0.573
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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