STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
whiB-6Transcriptional regulator WhiB4; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (100 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
  
 0.789
RN09_3513
Hypothetical protein.
  
     0.739
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 
 0.732
RN09_2255
HTH-type transcriptional regulator.
  
   
 0.730
whiA
Transcriptional regulator WhiA; Involved in cell division and chromosome segregation.
  
  
 0.690
SecG
Protein-export membrane protein SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
 
     0.677
whiB-5
Redox-responsive transcriptional regulator WhiB3; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
 
   
0.652
RN09_3916
Anti-sigma factor RshA.
 
 
 0.649
RN09_0643
Hypothetical protein.
  
     0.648
nucS
Endonuclease NucS; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
 
   
 0.621
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.