Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Cut5Putative cutinase. (233 aa)    
Predicted Functional Partners:
LprA
Lipoprotein LprA.
  
   
 0.735
RN09_4550
Oxidoreductase.
       0.679
RN09_0499
Membrane bound polyketide synthase; Overlaps another CDS with the same product name.
  
   0.678
RN09_1951
Hypothetical protein.
  
    0.602
PtbB
Phosphotyrosine protein phosphatase.
  
 
 0.597
RN09_1561
ABC transporter ATP-binding protein.
  
 0.584
Tbd2
ABC transporter ATP-binding protein.
  
 0.584
PpiA
Iron-regulated peptidyl-prolyl cis-trans isomerase PpiA; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
 0.582
PpiB
Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
 0.582
RN09_2149
ABC transporter ATP-binding protein/permease.
  
 0.574
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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