Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tadACytidine/deoxycytidylate deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (152 aa)    
Predicted Functional Partners:
RN09_4584
Hypothetical protein.
     
 0.878
dhmA-2
Haloalkane dehalogenase; Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
      0.834
TyrA
Prephenate dehydrogenase TyrA.
       0.752
rsmI
rRNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
  
 0.725
HbhA
Heparin binding hemagglutinin HbhA.
     
 0.668
hisE
phosphoribosyl-ATP pyrophosphatase.
   
  
 0.566
RN09_1730
Methyltransferase; Overlaps another CDS with the same product name; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
  
 0.558
GuaA
GMP synthase.
 
  
 0.551
rsfS
Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
     0.540
RN09_4184
Hypothetical protein.
 
  
 0.532
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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