RN09_4598 protein (Mycobacterium tuberculosis variant africanum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

RN09_4598

Two component sensor kinase TcrY; Overlaps another CDS with the same product name. (394 aa)

Predicted Functional Partners:

RN09_4597

0.993

RN09_4599

0.978

TrcR

0.880

PhoP

0.800

PrrA

0.790

RegX3

0.778

SucA

0.777

RN09_3491

0.772

TcrA

0.763

MprA

0.741

Your Current Organism:

Mycobacterium tuberculosis variant africanum

NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MprA	RN09_4597	RN09_1199	RN09_4597	Two-component response regulator MrpA.	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	0.885
MprA	RN09_4598	RN09_1199	RN09_4598	Two-component response regulator MrpA.	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	0.741
PhoP	RN09_4597	RN09_0935	RN09_4597	Two component system response transcriptional positive regulator PhoP.	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	0.887
PhoP	RN09_4598	RN09_0935	RN09_4598	Two component system response transcriptional positive regulator PhoP.	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	0.800
PrrA	RN09_4597	RN09_1106	RN09_4597	Two component transcriptional regulator PrrA.	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	0.890
PrrA	RN09_4598	RN09_1106	RN09_4598	Two component transcriptional regulator PrrA.	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	0.790
RN09_3491	RN09_4597	RN09_3491	RN09_4597	Transcriptional regulator.	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	0.842
RN09_3491	RN09_4598	RN09_3491	RN09_4598	Transcriptional regulator.	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	0.772
RN09_4597	MprA	RN09_4597	RN09_1199	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	Two-component response regulator MrpA.	0.885
RN09_4597	PhoP	RN09_4597	RN09_0935	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	Two component system response transcriptional positive regulator PhoP.	0.887
RN09_4597	PrrA	RN09_4597	RN09_1106	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	Two component transcriptional regulator PrrA.	0.890
RN09_4597	RN09_3491	RN09_4597	RN09_3491	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	Transcriptional regulator.	0.842
RN09_4597	RN09_4598	RN09_4597	RN09_4598	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	0.993
RN09_4597	RN09_4599	RN09_4597	RN09_4599	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	Two component transcriptional regulator TcrX.	0.979
RN09_4597	RegX3	RN09_4597	RN09_0599	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	Two component sensory transduction protein RegX.	0.890
RN09_4597	SucA	RN09_4597	RN09_1536	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	Putative 2-oxoglutarate dehydrogenase SUCA (alpha-ketoglutarate dehydrogenase); Multifunctional 2-oxoglutarate dehydrogenase E1 component /2-oxoglutarate dehydrogenase dihydrolipoyllysine-residue succinyltransferase.	0.777
RN09_4597	TcrA	RN09_4597	RN09_0744	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	Two component DNA binding transcriptional regulator TcrA.	0.887
RN09_4597	TrcR	RN09_4597	RN09_1277	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	Two component transcriptional regulator TrcR.	0.894
RN09_4598	MprA	RN09_4598	RN09_1199	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	Two-component response regulator MrpA.	0.741
RN09_4598	PhoP	RN09_4598	RN09_0935	Two component sensor kinase TcrY; Overlaps another CDS with the same product name.	Two component system response transcriptional positive regulator PhoP.	0.800