Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_4599Two component transcriptional regulator TcrX. (234 aa)    
Predicted Functional Partners:
RN09_4597
Two component sensor kinase TcrY; Overlaps another CDS with the same product name.
 
 
 0.979
RN09_4598
Two component sensor kinase TcrY; Overlaps another CDS with the same product name.
 
 
 0.978
TrcS
Two component sensor histidine kinase TrcS.
 
 
 0.904
SenX3
Two component sensor histidine kinase SenX3.
 
 
 0.892
PrrB
Two component sensor histidine kinase PrrB.
 
 
 0.878
PhoR
Two component system response sensor kinase PhoR.
 
 
 0.869
RN09_0742
Two component sensor kinase HK1.
 
 
 0.859
MprB
Two component histidine-protein kinase/phosphatase MprB; Overlaps another CDS with the same product name.
 
 
 0.852
MtrB
Two component sensory histidine kinase MtrB.
 
 
 0.810
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.768
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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