Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RN09_4601S-adenosylmethionine-dependent methyltransferase; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. (314 aa)    
Predicted Functional Partners:
RN09_3344
Hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
  
     0.766
RN09_4602
Hypothetical protein.
       0.552
RN09_4604
Hypothetical protein.
       0.502
RN09_4603
Hypothetical protein.
       0.496
RN09_4257
Hypothetical protein.
  
     0.486
purS
Hypothetical protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the am [...]
      
 0.418
RN09_2143
Hypothetical protein.
      
 0.418
RN09_3463
Short-chain type dehydrogenase/reductase.
      
 0.418
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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