Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_4682Dehydrogenase. (536 aa)    
Predicted Functional Partners:
RN09_4683
TetR family transcriptional regulator.
 
   
 0.909
RN09_2311
Hypothetical protein.
  
   
 0.721
PhyA
Phytoene synthase.
 
  
 0.693
RN09_4680
Transposase.
       0.678
RN09_4681
Resolvase.
       0.678
RN09_2859
Hypothetical protein.
      
 0.672
RN09_2005
Mannosyltransferase.
  
     0.598
RN09_0061
Membrane protein.
  
     0.578
RN09_0907
anti-sigma-L factor RslA.
  
     0.578
RN09_1668
HTH-type transcriptional regulator.
  
     0.568
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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