Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_4728ESX-1 secretion system protein EccCa. (747 aa)    
Predicted Functional Partners:
RN09_4727
ESX-1 secretion system protein EccB.
 
 
 0.995
RN09_4729
ESX-1 secretion system protein EccCb.
  
0.990
RN09_0349
ESX-3 secretion system protein EccC3; Overlaps another CDS with the same product name.
 
     0.948
RN09_4726
ESX-1 secretion system protein EccA1.
 
  
 0.938
RN09_4738
ESX-1 secretion system protein EccD1; Overlaps another CDS with the same product name.
 
 
 0.864
EsxA
ESAT-6 protein EsxA; Belongs to the WXG100 family.
 
 
 0.837
RN09_4725
ESX-1 secretion-associated protein EspH.
  
  
 0.827
RN09_4722
ESX-1 secretion-associated protein EspF.
       0.813
RN09_4744
ESX-1 secretion system protein EccE1.
  
 
 
 0.805
RN09_4224
ESX-4 secretion system protein EccB4.
 
 
 0.756
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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