STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EsxAESAT-6 protein EsxA; Belongs to the WXG100 family. (95 aa)    
Predicted Functional Partners:
EsxB
ESAT-6-like protein EsxB.
  
 
 0.999
RN09_4738
ESX-1 secretion system protein EccD1; Overlaps another CDS with the same product name.
 
   
 0.893
PhoP
Two component system response transcriptional positive regulator PhoP.
     
 0.890
RN09_4721
ESX-1 secretion-associated protein EspE.
 
 
 0.887
RN09_4433
ESX-1 secretion-associated protein EspA.
  
 
 0.865
groL
Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
      
 0.859
RN09_4744
ESX-1 secretion system protein EccE1.
 
   
 0.857
FbpB
Diacylglycerol acyltransferase/mycolyltransferase Ag85B.
   
  
 0.853
RN09_4743
ESX-1 secretion-associated protein EspB.
  
  
 0.849
RN09_4432
ESX-1 secretion-associated protein EspC.
      
 0.846
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.