Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_4740ESX-1 secretion-associated protein EspK. (391 aa)    
Predicted Functional Partners:
RN09_4741
ESX-1 secretion-associated protein EspK.
  
   0.749
RN09_4739
ESX-1 secretion-associated protein EspJ.
  
 
 0.731
RN09_4743
ESX-1 secretion-associated protein EspB.
  
  
 0.612
RN09_4729
ESX-1 secretion system protein EccCb.
    
 
 0.611
RN09_4736
ESX-1 secretion-associated protein EspI.
  
  
 0.581
EsxB
ESAT-6-like protein EsxB.
   
 
 0.533
RN09_4737
ESX-1 secretion system protein EccD1; Overlaps another CDS with the same product name.
   
 
 0.501
EsxA
ESAT-6 protein EsxA; Belongs to the WXG100 family.
   
 
 0.485
MycP1
Membrane-anchored mycosin.
  
 
 0.479
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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