Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RN09_4744ESX-1 secretion system protein EccE1. (462 aa)    
Predicted Functional Partners:
MycP1
Membrane-anchored mycosin.
 
  
 0.985
RN09_4727
ESX-1 secretion system protein EccB.
 
 
 
 0.912
EsxA
ESAT-6 protein EsxA; Belongs to the WXG100 family.
 
   
 0.844
RN09_4743
ESX-1 secretion-associated protein EspB.
     
 0.827
RN09_4738
ESX-1 secretion system protein EccD1; Overlaps another CDS with the same product name.
 
   
 0.814
RN09_4728
ESX-1 secretion system protein EccCa.
  
 
 
 0.805
RN09_4742
ESX-1 secretion-associated protein EspL; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the YbaB/EbfC family.
     
 0.778
RN09_4746
ESX-2 secretion system protein EccA.
  
  
 0.751
RN09_2210
ESX-5 type VII secretion system protein EccD.
  
 
 0.725
IniB
Isoniazid inducible protein IniB.
  
     0.720
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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