Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MycP1Membrane-anchored mycosin. (456 aa)    
Predicted Functional Partners:
RN09_4744
ESX-1 secretion system protein EccE1.
 
  
 0.985
RN09_4743
ESX-1 secretion-associated protein EspB.
  
  
 0.858
RN09_4746
ESX-2 secretion system protein EccA.
  
  
 0.784
RN09_4727
ESX-1 secretion system protein EccB.
 
 
 0.761
RN09_0347
ESX-3 secretion system protein EccB3.
 
 
 0.681
RN09_4742
ESX-1 secretion-associated protein EspL; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the YbaB/EbfC family.
     
 0.654
RN09_4224
ESX-4 secretion system protein EccB4.
 
 
 0.597
RN09_4728
ESX-1 secretion system protein EccCa.
 
 
 0.571
RN09_4221
ESX-4 secretion system protein EccC4; Overlaps another CDS with the same product name.
 
 
 0.540
RN09_4729
ESX-1 secretion system protein EccCb.
 
 
 0.523
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.