Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EsxEESAT-6 like protein EsxE; Belongs to the WXG100 family. (96 aa)    
Predicted Functional Partners:
EsxF
ESAT-6 like protein EsxF; Belongs to the WXG100 family.
  
  
 0.982
RN09_4774
Alanine/proline-rich protein; Overlaps another CDS with the same product name.
  
  
 0.948
RN09_4773
Hypothetical protein.
     
 0.875
EsxU
ESAT-6 like protein EsxU; Belongs to the WXG100 family.
  
 
 0.819
RN09_3873
Hypothetical protein.
  
 
 0.809
EsxB
ESAT-6-like protein EsxB.
  
 
 0.808
RN09_4775
Alanine/proline-rich protein; Overlaps another CDS with the same product name.
       0.783
RN09_4778
Hypothetical protein.
  
 
 0.672
mca
Mycothiol S-conjugate amidase; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
      
 0.671
MycP4
Membrane-anchored mycosin; Belongs to the peptidase S8 family.
  
  
 0.659
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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