Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TrxB2Thioredoxin reductase. (335 aa)    
Predicted Functional Partners:
TrxC
Thioredoxin TrxC; Belongs to the thioredoxin family.
 
 0.998
TrxB1
Thioredoxin; Belongs to the thioredoxin family.
 
 0.995
AhpC
Alkyl hydroperoxide reductase subunit C.
  
 
 0.916
TrxA
Thioredoxin TrxA.
  
 
 0.914
Csd
Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
 
  0.909
ThiX
Thioredoxin ThiX.
  
 
 0.878
RN09_1635
Thioredoxin.
  
 
 0.842
DipZ
Integral membrane C-type cytochrome biogenesis protein DipZ.
  
 
 0.741
RN09_4791
Peptidoglycan hydrolase.
  
  
 0.709
RN09_4786
ECF RNA polymerase sigma factor SigM; Belongs to the sigma-70 factor family. ECF subfamily.
     
 0.658
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
Server load: low (14%) [HD]