Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ORV92336.1CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CoA-transferase III family. (401 aa)    
Predicted Functional Partners:
ORV92337.1
hydroxymethylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.897
ORV92340.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.816
sucD
succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 0.802
ORV92338.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.795
ORV92334.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.793
sucC
succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.792
ORV92335.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.791
ORV92465.1
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.763
ORV92341.1
DUF4440 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.757
ORV92466.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0312 family.
       0.748
Your Current Organism:
Mycobacterium interjectum
NCBI taxonomy Id: 33895
Other names: ATCC 51457, CCUG 37514, DSM 44064, M. interjectum, strain 4185/92
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