close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppro_0069PTS IIA-like nitrogen-regulatory protein PtsN; TIGRFAM: DNA binding domain, excisionase family; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: gme:Gmet_2604 putative PTS IIA-like nitrogen-regulatory protein PtsN. (225 aa)    
Predicted Functional Partners:
Ppro_0980
TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: gme:Gmet_1288 HPrNtr.
 
  
 0.874
Ppro_0977
Uncharacterized P-loop ATPase protein UPF0042; Displays ATPase and GTPase activities.
  
  
 0.820
Ppro_0981
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.817
hpf
SSU ribosomal protein S30P / sigma 54 modulation protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
 
  
 0.816
Ppro_0070
NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: gsu:GSU0734 NAD-dependent dehydrogenase subunit.
 
     0.814
Ppro_2232
PTSINtr with GAF domain, PtsP; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; GAF domain protein; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein; KEGG: gme:Gmet_2404 putative GAF sensor protein; Belongs to the PEP-utilizing enzyme family.
 
   
 0.811
Ppro_0978
PFAM: PTS system fructose subfamily IIA component; KEGG: gme:Gmet_1287 PTS system fructose subfamily IIA component.
 
  
 0.798
hprK
Hpr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
 
  
 0.598
Ppro_0974
RNA polymerase, sigma 54 subunit, RpoN/SigL; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.563
Ppro_1449
Transcriptional regulator, DeoR family; PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein; KEGG: pca:Pcar_0940 transcriptional regulator, DeoR family.
 
  
 0.561
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
Server load: low (18%) [HD]