STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppro_0189PFAM: protein of unknown function DUF159; KEGG: ava:Ava_3892 protein of unknown function DUF159; Belongs to the SOS response-associated peptidase family. (238 aa)    
Predicted Functional Partners:
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
   
 0.818
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
       0.784
Ppro_0191
KEGG: gsu:GSU0042 hypothetical protein.
       0.773
Ppro_0196
PFAM: metal-dependent phosphohydrolase, HD sub domain; KEGG: gsu:GSU2123 HD domain protein.
       0.553
Ppro_0193
PFAM: Lytic transglycosylase, catalytic; KEGG: gsu:GSU2121 transglycosylase SLT domain protein.
       0.541
Ppro_0194
KEGG: sat:SYN_01885 hypothetical cytosolic protein.
       0.541
Ppro_0195
KEGG: gsu:GSU2122 TraG family protein.
       0.541
Ppro_0197
PFAM: glutaredoxin 2; KEGG: gsu:GSU2124 thioredoxin-related domain protein.
       0.541
Ppro_0198
KEGG: gsu:GSU2125 hypothetical protein.
       0.456
Ppro_0199
KEGG: gsu:GSU2126 hypothetical protein.
       0.421
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.