STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppro_0302Methylthioadenosine nucleosidase; PFAM: purine and other phosphorylases, family 1; KEGG: gsu:GSU1897 MTA/SAH nucleosidase, putative. (241 aa)    
Predicted Functional Partners:
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.916
mtnP
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
    
 0.914
Ppro_3437
PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: gsu:GSU0421 flagellar motor switch protein FliM.
    
   0.703
mqnB
Methylthioadenosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).
  
     0.695
Ppro_1189
Squalene-hopene cyclase; KEGG: gme:Gmet_2820 terpene synthase:squalene cyclase; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase.
 
   
 0.552
Ppro_0765
TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; KEGG: gsu:GSU3061 squalene-hopene cyclase.
 
   
 0.535
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.518
Ppro_3242
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.510
Ppro_0283
PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: gme:Gmet_0504 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein.
     
 0.507
Ppro_1192
PFAM: Radical SAM domain protein; KEGG: gsu:GSU0685 radical SAM domain protein.
 
   
 0.439
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.