STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppro_0436PFAM: UspA domain protein; KEGG: gme:Gmet_2678 UspA. (151 aa)    
Predicted Functional Partners:
Ppro_0437
Response regulator receiver sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: gsu:GSU1119 sensor histidine kinase/response regulator.
  
    0.820
Ppro_0435
PFAM: response regulator receiver; KEGG: gme:Gmet_2679 response regulator receiver domain protein (CheY-like).
  
  
 0.740
Ppro_3112
PFAM: UspA domain protein; KEGG: mac:MA3944 universal stress protein.
  
     0.595
Ppro_0439
PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: gme:Gmet_2676 FAD dependent oxidoreductase.
       0.555
Ppro_1338
methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
    0.546
Ppro_1991
Multi-sensor signal transduction histidine kinase; KEGG: gsu:GSU2444 sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein; extracellular solute-binding protein, family 3.
  
 
 0.514
Ppro_2657
KEGG: gme:Gmet_1232 hypothetical protein.
 
    0.511
Ppro_0438
PFAM: response regulator receiver; KEGG: gsu:GSU1120 response regulator.
  
  
 0.488
Ppro_0433
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: gsu:GSU1114 TPR domain protein.
       0.479
hpf
SSU ribosomal protein S30P / sigma 54 modulation protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
   
  
 0.467
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
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