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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppro_1025PFAM: Transketolase, central region; Transketolase domain protein; KEGG: reu:Reut_B5551 transketolase, central region:transketolase, C-terminal. (333 aa)    
Predicted Functional Partners:
Ppro_1024
Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component; KEGG: pca:Pcar_0343 acetoin dehydrogenase complex, E1 component, alpha subunit.
 0.999
Ppro_1026
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; KEGG: pca:Pcar_0345 dehydrogenase complex E2 component, dihydrolipamide acetyltransferase.
 
 0.999
Ppro_1027
Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component; KEGG: pca:Pcar_0343 acetoin dehydrogenase complex, E1 component, alpha subunit.
 0.999
Ppro_1030
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: pca:Pcar_0347 2-oxoglutarate dehydrogenase complex, E3 component, lipoamide dehydrogenase.
 
 0.996
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.975
Ppro_2238
PFAM: biotin/lipoate A/B protein ligase; KEGG: gme:Gmet_3151 biotin/lipoate A/B protein ligase.
 
 
 0.878
Ppro_1038
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
  
 0.822
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 
 0.729
gcvH-2
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 
 0.729
Ppro_1587
TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; KEGG: gme:Gmet_3155 glycine cleavage system T protein.
     
 0.681
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
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