STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppro_1779PFAM: Ppx/GppA phosphatase; KEGG: gme:Gmet_1828 Ppx/GppA phosphatase. (311 aa)    
Predicted Functional Partners:
Ppro_2399
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
 
 0.932
Ppro_1455
PFAM: RelA/SpoT domain protein; KEGG: sth:STH1636 putative GTP pyrophosphokinase.
     
  0.900
Ppro_2286
PFAM: RelA/SpoT domain protein; KEGG: hypothetical protein.
     
  0.900
Ppro_2029
Polyphosphate kinase-like protein; KEGG: gme:Gmet_0133 polyphosphate kinase.
 
  
 0.865
Ppro_1780
PFAM: Na+/Pi-cotransporter; KEGG: gsu:GSU1742 Na/Pi-cotransporter family protein.
       0.802
rnc
RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
     
 0.777
Ppro_1777
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gme:Gmet_2316 radical SAM.
       0.773
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
 
 
    0.582
Ppro_1781
PFAM: histone family protein DNA-binding protein; KEGG: gme:Gmet_1833 histone-like DNA-binding protein; Belongs to the bacterial histone-like protein family.
       0.572
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.531
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
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