STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppro_1925Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bxe:Bxe_B0452 transcriptional regulator, LysR family. (296 aa)    
Predicted Functional Partners:
Ppro_0729
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; KEGG: gme:Gmet_0147 ferredoxin-dependent glutamate synthase.
  
  
 0.576
Ppro_2159
Glutamate synthase (NADPH) GltB3 subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; glutamate synthase, alpha subunit domain protein; KEGG: pca:Pcar_2600 pyridine nucleotide-disulfide oxidoreductase.
  
 
 0.573
Ppro_1926
KEGG: gsu:GSU1903 3-isopropylmalate dehydratase, large subunit, putative; TIGRFAM: homoaconitate hydratase family protein; 3-isopropylmalate dehydratase; PFAM: aconitate hydratase domain protein.
  
  
 0.568
Ppro_0775
PFAM: iron dependent repressor; FeoA family protein; KEGG: gsu:GSU1382 iron-dependent repressor, putative.
  
 
 0.516
Ppro_0283
PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: gme:Gmet_0504 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein.
  
  
 0.445
Ppro_1927
3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: gsu:GSU1902 3-isopropylmalate dehydratase, small subunit, putative.
     
 0.444
msrA
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.404
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
      
 0.403
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.402
Ppro_1991
Multi-sensor signal transduction histidine kinase; KEGG: gsu:GSU2444 sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein; extracellular solute-binding protein, family 3.
   
  
 0.400
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
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