Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ppro_2575KEGG: aba:Acid345_1077 guanosine polyphosphate pyrophosphohydrolases/synthetases. (448 aa)    
Predicted Functional Partners:
rpsP
PFAM: ribosomal protein S16; KEGG: gsu:GSU0643 ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
 
 
   0.830
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.830
rpsL
SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy.
   
 
 0.825
rpmI
PFAM: ribosomal protein L35; KEGG: gme:Gmet_1413 ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
   
 
 0.825
rplK
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
 
 0.819
rpsE
SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
   
 
 0.816
rpsI
PFAM: ribosomal protein S9; KEGG: pca:Pcar_1899 ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.816
rplB
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
   0.809
rpmB
PFAM: ribosomal protein L28; KEGG: gsu:GSU2234 ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
   0.809
rplU
LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
    
 
 0.808
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
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