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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppro_3076PFAM: heat shock protein Hsp20; CS; KEGG: gme:Gmet_2986 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. (148 aa)    
Predicted Functional Partners:
clpB
ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
 
 
 0.830
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 
 0.606
Ppro_3075
KEGG: gme:Gmet_2927 hypothetical protein.
       0.557
Ppro_0314
PFAM: heat shock protein Hsp20; KEGG: gsu:GSU2409 heat shock protein, HSP20 family; Belongs to the small heat shock protein (HSP20) family.
 
   
0.502
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.480
Ppro_0157
PFAM: Heat shock protein 70; KEGG: cdi:DIP2120 chaperone protein DnaK.
  
 
 0.469
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.469
Ppro_2145
KEGG: ade:Adeh_2261 molecular chaperone-like.
  
 
 0.461
Ppro_3077
tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
       0.450
Ppro_0315
PFAM: heat shock protein Hsp20; KEGG: gsu:GSU2410 heat shock protein, HSP20 family; Belongs to the small heat shock protein (HSP20) family.
  
   
0.445
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
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