STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mqnDProtein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (284 aa)    
Predicted Functional Partners:
mqnC
Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
  
 0.981
mqnA
Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
   
 0.874
Ppro_0290
TIGRFAM: 4-hydroxybenzoate polyprenyltransferase, putative; PFAM: UbiA prenyltransferase; KEGG: gsu:GSU0439 4-hydroxybenzoate octaprenyltransferase, putative; Belongs to the UbiA prenyltransferase family.
 
   
 0.815
mqnE
Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
 
   
 0.810
Ppro_2237
PFAM: Carboxylyase-related protein; KEGG: gme:Gmet_0993 carboxylyase-related protein; Belongs to the UbiD family.
  
   
 0.791
Ppro_0291
TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: gsu:GSU0437 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family.
  
   
 0.761
mqnB
Methylthioadenosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
   
 0.756
ubiX
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
 
   
 0.726
Ppro_3280
PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: bja:blr2848 probable sulphate transport protein.
       0.598
Ppro_3409
PFAM: amidohydrolase; Amidohydrolase 3; KEGG: gme:Gmet_1645 chlorohydrolase, Atz/Trz family.
  
     0.591
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.