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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppro_3483PFAM: AMP-dependent synthetase and ligase; KEGG: gme:Gmet_1469 AMP-dependent synthetase and ligase. (620 aa)    
Predicted Functional Partners:
Ppro_2870
PFAM: AMP-dependent synthetase and ligase; KEGG: mhu:Mhun_3158 AMP-dependent synthetase and ligase.
 
 
0.938
rplE
LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
 
 0.810
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.787
Ppro_3481
PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: bxe:Bxe_A4347 two component transcriptional regulator, LuxR family.
       0.773
Ppro_3482
KEGG: sat:SYN_01954 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
       0.773
rplR
LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
    
 
 0.768
Ppro_3101
PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; KR; KEGG: son:SO1602 multi-domain beta-ketoacyl synthase.
  
 
 0.580
Ppro_3277
PFAM: Ankyrin; KEGG: gme:Gmet_0162 ankyrin.
   
 0.546
Ppro_3480
PFAM: response regulator receiver; KEGG: gsu:GSU1891 response regulator.
 
     0.544
Ppro_0094
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: bur:Bcep18194_C7186 3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.538
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
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