Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Rfer_0601PTS system fructose subfamily IIA component. (148 aa)    
Predicted Functional Partners:
Rfer_0602
HPrNtr.
 
 0.994
Rfer_0603
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.927
Rfer_0711
Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.919
Rfer_2999
Phosphomannomutase.
    
 0.908
Rfer_1122
Mannose-6-phosphate isomerase, type II.
    
 0.906
Rfer_1904
PfkB.
  
 
 0.824
Rfer_0673
GDP-mannose 6-dehydrogenase.
    
  0.801
Rfer_0751
PTS IIA-like nitrogen-regulatory protein PtsN.
 
  
 0.735
Rfer_0952
Binding-protein-dependent transport systems inner membrane component.
   
  
 0.641
Rfer_1102
Beta-glucosidase. Glycosyl Hydrolase family 1.
      
 0.636
Your Current Organism:
Rhodoferax ferrireducens
NCBI taxonomy Id: 338969
Other names: Albidiferax ferrireducens T118, R. ferrireducens T118, Rhodoferax ferrireducens ATCC BAA-621, Rhodoferax ferrireducens DSM 15236, Rhodoferax ferrireducens T118, Rhodoferax ferrireducens str. T118, Rhodoferax ferrireducens strain T118
Server load: low (18%) [HD]