| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rfer_0189 | Rfer_2014 | Rfer_0189 | Rfer_2014 | Peptidase M22, glycoprotease. | GCN5-related N-acetyltransferase. | 0.479 |
| Rfer_0189 | guaA | Rfer_0189 | Rfer_2287 | Peptidase M22, glycoprotease. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.450 |
| Rfer_2012 | Rfer_2014 | Rfer_2012 | Rfer_2014 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GCN5-related N-acetyltransferase. | 0.671 |
| Rfer_2012 | Rfer_2015 | Rfer_2012 | Rfer_2015 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Conserved hypothetical protein. | 0.479 |
| Rfer_2012 | ftsH | Rfer_2012 | Rfer_2011 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.781 |
| Rfer_2012 | glmM | Rfer_2012 | Rfer_2013 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.890 |
| Rfer_2014 | Rfer_0189 | Rfer_2014 | Rfer_0189 | GCN5-related N-acetyltransferase. | Peptidase M22, glycoprotease. | 0.479 |
| Rfer_2014 | Rfer_2012 | Rfer_2014 | Rfer_2012 | GCN5-related N-acetyltransferase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.671 |
| Rfer_2014 | Rfer_2015 | Rfer_2014 | Rfer_2015 | GCN5-related N-acetyltransferase. | Conserved hypothetical protein. | 0.565 |
| Rfer_2014 | ftsH | Rfer_2014 | Rfer_2011 | GCN5-related N-acetyltransferase. | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.528 |
| Rfer_2014 | glmM | Rfer_2014 | Rfer_2013 | GCN5-related N-acetyltransferase. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.822 |
| Rfer_2014 | guaA | Rfer_2014 | Rfer_2287 | GCN5-related N-acetyltransferase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.498 |
| Rfer_2015 | Rfer_2012 | Rfer_2015 | Rfer_2012 | Conserved hypothetical protein. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.479 |
| Rfer_2015 | Rfer_2014 | Rfer_2015 | Rfer_2014 | Conserved hypothetical protein. | GCN5-related N-acetyltransferase. | 0.565 |
| Rfer_2015 | glmM | Rfer_2015 | Rfer_2013 | Conserved hypothetical protein. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.565 |
| ftsH | Rfer_2012 | Rfer_2011 | Rfer_2012 | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.781 |
| ftsH | Rfer_2014 | Rfer_2011 | Rfer_2014 | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | GCN5-related N-acetyltransferase. | 0.528 |
| ftsH | glmM | Rfer_2011 | Rfer_2013 | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.661 |
| ftsH | guaA | Rfer_2011 | Rfer_2287 | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.448 |
| glmM | Rfer_2012 | Rfer_2013 | Rfer_2012 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.890 |