| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rfer_0760 | Rfer_2102 | Rfer_0760 | Rfer_2102 | DNA polymerase III, delta subunit. | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.542 |
| Rfer_0760 | Rfer_2968 | Rfer_0760 | Rfer_2968 | DNA polymerase III, delta subunit. | Stringent starvation protein B. | 0.732 |
| Rfer_0760 | bamE | Rfer_0760 | Rfer_0754 | DNA polymerase III, delta subunit. | SmpA/OmlA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.852 |
| Rfer_0760 | cca | Rfer_0760 | Rfer_1090 | DNA polymerase III, delta subunit. | Metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.552 |
| Rfer_2100 | Rfer_2102 | Rfer_2100 | Rfer_2102 | NLP/P60. | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.757 |
| Rfer_2100 | Rfer_2103 | Rfer_2100 | Rfer_2103 | NLP/P60. | Hypothetical protein. | 0.523 |
| Rfer_2100 | mnmC | Rfer_2100 | Rfer_2101 | NLP/P60. | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity); In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. | 0.773 |
| Rfer_2102 | Rfer_0760 | Rfer_2102 | Rfer_0760 | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | DNA polymerase III, delta subunit. | 0.542 |
| Rfer_2102 | Rfer_2100 | Rfer_2102 | Rfer_2100 | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | NLP/P60. | 0.757 |
| Rfer_2102 | Rfer_2103 | Rfer_2102 | Rfer_2103 | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Hypothetical protein. | 0.548 |
| Rfer_2102 | Rfer_2968 | Rfer_2102 | Rfer_2968 | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Stringent starvation protein B. | 0.663 |
| Rfer_2102 | bamE | Rfer_2102 | Rfer_0754 | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | SmpA/OmlA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.605 |
| Rfer_2102 | cca | Rfer_2102 | Rfer_1090 | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.590 |
| Rfer_2102 | dsbB | Rfer_2102 | Rfer_2104 | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Disulphide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. | 0.501 |
| Rfer_2102 | mnmC | Rfer_2102 | Rfer_2101 | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity); In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. | 0.800 |
| Rfer_2102 | rpiA | Rfer_2102 | Rfer_2206 | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.535 |
| Rfer_2102 | rpmF | Rfer_2102 | Rfer_1728 | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | LSU ribosomal protein L32P; Belongs to the bacterial ribosomal protein bL32 family. | 0.525 |
| Rfer_2103 | Rfer_2100 | Rfer_2103 | Rfer_2100 | Hypothetical protein. | NLP/P60. | 0.523 |
| Rfer_2103 | Rfer_2102 | Rfer_2103 | Rfer_2102 | Hypothetical protein. | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.548 |
| Rfer_2103 | dsbB | Rfer_2103 | Rfer_2104 | Hypothetical protein. | Disulphide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. | 0.532 |