Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Rfer_2227Transcriptional regulator, XRE family. (1015 aa)    
Predicted Functional Partners:
Rfer_2284
Putative adenylate/guanylate cyclase.
 
   
 0.674
Rfer_3932
Diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(s).
     
 0.564
Rfer_2228
Globin.
       0.544
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.500
Rfer_1825
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s).
     
 0.498
Rfer_3942
Serine/threonine protein kinase with Chase2 sensor.
 
   
 0.497
Rfer_2229
Methyltransferase type 11.
  
  
 0.481
Rfer_2278
Transcriptional regulator, MerR family.
  
  
 0.467
Rfer_2294
Cystathionine beta-lyase.
  
  
 0.466
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
  
 0.466
Your Current Organism:
Rhodoferax ferrireducens
NCBI taxonomy Id: 338969
Other names: Albidiferax ferrireducens T118, R. ferrireducens T118, Rhodoferax ferrireducens ATCC BAA-621, Rhodoferax ferrireducens DSM 15236, Rhodoferax ferrireducens T118, Rhodoferax ferrireducens str. T118, Rhodoferax ferrireducens strain T118
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