STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rfer_2227Transcriptional regulator, XRE family. (1015 aa)    
Predicted Functional Partners:
Rfer_2284
Putative adenylate/guanylate cyclase.
 
   
 0.601
Rfer_0696
Regulatory protein, LuxR.
   
 
 0.553
Rfer_2228
Globin.
       0.543
Rfer_1768
Multi-sensor hybrid histidine kinase.
 
 
 0.524
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.509
Rfer_3475
Diguanylate cyclase with PAS/PAC sensor.
     
 0.487
Rfer_1061
Protein of unknown function DUF262.
     
 0.477
Rfer_2294
Cystathionine beta-lyase.
  
  
 0.475
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
  
 0.475
Rfer_3649
Methionine gamma-lyase.
  
  
 0.475
Your Current Organism:
Rhodoferax ferrireducens
NCBI taxonomy Id: 338969
Other names: Albidiferax ferrireducens T118, R. ferrireducens T118, Rhodoferax ferrireducens ATCC BAA-621, Rhodoferax ferrireducens DSM 15236, Rhodoferax ferrireducens T118, Rhodoferax ferrireducens str. T118, Rhodoferax ferrireducens strain T118
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.