Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rfer_2285Peptidase U61, LD-carboxypeptidase A. (351 aa)    
Predicted Functional Partners:
tadA
CMP/dCMP deaminase, zinc-binding; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
       0.817
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.706
Rfer_2284
Putative adenylate/guanylate cyclase.
       0.618
nagZ
Beta-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
 
   
 0.589
Rfer_0920
Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family.
    
 0.554
Rfer_2346
murein-DD-endopeptidase. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family.
    
 0.554
Rfer_3801
Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family.
    
 0.554
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.551
Rfer_2901
Putative inner membrane transmembrane protein.
  
     0.536
Rfer_0191
D-Ala-D-Ala carboxypeptidase PBP3. Serine peptidase. MEROPS family S13.
 
   
 0.497
Your Current Organism:
Rhodoferax ferrireducens
NCBI taxonomy Id: 338969
Other names: Albidiferax ferrireducens T118, R. ferrireducens T118, Rhodoferax ferrireducens ATCC BAA-621, Rhodoferax ferrireducens DSM 15236, Rhodoferax ferrireducens T118, Rhodoferax ferrireducens str. T118, Rhodoferax ferrireducens strain T118
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