| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rfer_0121 | Rfer_2865 | Rfer_0121 | Rfer_2865 | Alcohol dehydrogenase, zinc-binding; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Iron-containing alcohol dehydrogenase. | 0.965 |
| Rfer_0121 | tadA | Rfer_0121 | Rfer_2286 | Alcohol dehydrogenase, zinc-binding; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | CMP/dCMP deaminase, zinc-binding; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.966 |
| Rfer_0189 | guaA | Rfer_0189 | Rfer_2287 | Peptidase M22, glycoprotease. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.450 |
| Rfer_0189 | tadA | Rfer_0189 | Rfer_2286 | Peptidase M22, glycoprotease. | CMP/dCMP deaminase, zinc-binding; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.748 |
| Rfer_2145 | Rfer_2259 | Rfer_2145 | Rfer_2259 | AMP-dependent synthetase and ligase. | Ankyrin. | 0.857 |
| Rfer_2145 | gpsA | Rfer_2145 | Rfer_1313 | AMP-dependent synthetase and ligase. | Glycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.596 |
| Rfer_2145 | guaA | Rfer_2145 | Rfer_2287 | AMP-dependent synthetase and ligase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.474 |
| Rfer_2145 | guaB | Rfer_2145 | Rfer_2288 | AMP-dependent synthetase and ligase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.409 |
| Rfer_2145 | tadA | Rfer_2145 | Rfer_2286 | AMP-dependent synthetase and ligase. | CMP/dCMP deaminase, zinc-binding; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.782 |
| Rfer_2259 | Rfer_2145 | Rfer_2259 | Rfer_2145 | Ankyrin. | AMP-dependent synthetase and ligase. | 0.857 |
| Rfer_2259 | guaB | Rfer_2259 | Rfer_2288 | Ankyrin. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.447 |
| Rfer_2259 | tadA | Rfer_2259 | Rfer_2286 | Ankyrin. | CMP/dCMP deaminase, zinc-binding; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.741 |
| Rfer_2285 | guaA | Rfer_2285 | Rfer_2287 | Peptidase U61, LD-carboxypeptidase A. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.723 |
| Rfer_2285 | guaB | Rfer_2285 | Rfer_2288 | Peptidase U61, LD-carboxypeptidase A. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.551 |
| Rfer_2285 | tadA | Rfer_2285 | Rfer_2286 | Peptidase U61, LD-carboxypeptidase A. | CMP/dCMP deaminase, zinc-binding; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.824 |
| Rfer_2865 | Rfer_0121 | Rfer_2865 | Rfer_0121 | Iron-containing alcohol dehydrogenase. | Alcohol dehydrogenase, zinc-binding; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.965 |
| Rfer_2865 | tadA | Rfer_2865 | Rfer_2286 | Iron-containing alcohol dehydrogenase. | CMP/dCMP deaminase, zinc-binding; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.910 |
| gpsA | Rfer_2145 | Rfer_1313 | Rfer_2145 | Glycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | AMP-dependent synthetase and ligase. | 0.596 |
| gpsA | tadA | Rfer_1313 | Rfer_2286 | Glycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | CMP/dCMP deaminase, zinc-binding; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.708 |
| guaA | Rfer_0189 | Rfer_2287 | Rfer_0189 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Peptidase M22, glycoprotease. | 0.450 |