Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Rfer_2848thiamineS. (84 aa)    
Predicted Functional Partners:
Rfer_1917
Molybdopterin synthase subunit MoaE.
  
 0.995
Rfer_1307
UBA/THIF-type NAD/FAD binding protein.
  
 0.950
Rfer_2849
FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
  
 0.940
Rfer_2850
Phenylacetaldehyde:ferredoxin oxidoreductase.
 
     0.909
Rfer_1916
Molybdopterin synthase subunit MoaD.
     
  0.900
Rfer_2851
4Fe-4S ferredoxin, iron-sulfur binding.
 
   
 0.883
moaC
GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
  
 0.868
Rfer_2223
FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
  
 0.768
Rfer_2847
Hypothetical protein.
       0.643
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
  
 0.625
Your Current Organism:
Rhodoferax ferrireducens
NCBI taxonomy Id: 338969
Other names: Albidiferax ferrireducens T118, R. ferrireducens T118, Rhodoferax ferrireducens ATCC BAA-621, Rhodoferax ferrireducens DSM 15236, Rhodoferax ferrireducens T118, Rhodoferax ferrireducens str. T118, Rhodoferax ferrireducens strain T118
Server load: low (40%) [HD]