| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rfer_2890 | Rfer_2891 | Rfer_2890 | Rfer_2891 | Serine O-acetyltransferase. | RNA methyltransferase TrmH, group 1. | 0.819 |
| Rfer_2890 | Rfer_2892 | Rfer_2890 | Rfer_2892 | Serine O-acetyltransferase. | Inositol-1(or 4)-monophosphatase. | 0.602 |
| Rfer_2891 | Rfer_2890 | Rfer_2891 | Rfer_2890 | RNA methyltransferase TrmH, group 1. | Serine O-acetyltransferase. | 0.819 |
| Rfer_2891 | Rfer_2892 | Rfer_2891 | Rfer_2892 | RNA methyltransferase TrmH, group 1. | Inositol-1(or 4)-monophosphatase. | 0.697 |
| Rfer_2891 | Rfer_2968 | Rfer_2891 | Rfer_2968 | RNA methyltransferase TrmH, group 1. | Stringent starvation protein B. | 0.479 |
| Rfer_2891 | dksA | Rfer_2891 | Rfer_3438 | RNA methyltransferase TrmH, group 1. | Transcriptional regulators, TraR/DksA family; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. | 0.466 |
| Rfer_2891 | dusA | Rfer_2891 | Rfer_1943 | RNA methyltransferase TrmH, group 1. | TIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | 0.502 |
| Rfer_2891 | rlmE | Rfer_2891 | Rfer_2010 | RNA methyltransferase TrmH, group 1. | Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.571 |
| Rfer_2891 | rnhB | Rfer_2891 | Rfer_2002 | RNA methyltransferase TrmH, group 1. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.611 |
| Rfer_2891 | rsmA | Rfer_2891 | Rfer_0096 | RNA methyltransferase TrmH, group 1. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.453 |
| Rfer_2891 | trmB | Rfer_2891 | Rfer_1896 | RNA methyltransferase TrmH, group 1. | Conserved hypothetical protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.451 |
| Rfer_2891 | truB | Rfer_2891 | Rfer_2136 | RNA methyltransferase TrmH, group 1. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.428 |
| Rfer_2892 | Rfer_2890 | Rfer_2892 | Rfer_2890 | Inositol-1(or 4)-monophosphatase. | Serine O-acetyltransferase. | 0.602 |
| Rfer_2892 | Rfer_2891 | Rfer_2892 | Rfer_2891 | Inositol-1(or 4)-monophosphatase. | RNA methyltransferase TrmH, group 1. | 0.697 |
| Rfer_2968 | Rfer_2891 | Rfer_2968 | Rfer_2891 | Stringent starvation protein B. | RNA methyltransferase TrmH, group 1. | 0.479 |
| dksA | Rfer_2891 | Rfer_3438 | Rfer_2891 | Transcriptional regulators, TraR/DksA family; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. | RNA methyltransferase TrmH, group 1. | 0.466 |
| dksA | rlmE | Rfer_3438 | Rfer_2010 | Transcriptional regulators, TraR/DksA family; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. | Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.655 |
| dusA | Rfer_2891 | Rfer_1943 | Rfer_2891 | TIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | RNA methyltransferase TrmH, group 1. | 0.502 |
| dusA | rlmE | Rfer_1943 | Rfer_2010 | TIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.494 |
| dusA | trmB | Rfer_1943 | Rfer_1896 | TIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | Conserved hypothetical protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.439 |