Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rfer_3291Respiratory-chain NADH dehydrogenase, subunit 1. (316 aa)    
Predicted Functional Partners:
Rfer_3288
NADH-ubiquinone oxidoreductase, chain 49kDa.
 
 
 0.997
Rfer_3281
NADH ubiquinone oxidoreductase, 20 kDa subunit.
 
 
 0.996
Rfer_3287
NADH ubiquinone oxidoreductase, 20 kDa subunit.
 
 
 0.990
Rfer_3280
NADH-ubiquinone oxidoreductase, chain 49kDa.
 
 
 0.986
Rfer_3292
NADH dehydrogenase (quinone).
 
 
 0.980
Rfer_3289
NADH dehydrogenase (quinone).
 
 
 0.979
Rfer_3290
Hydrogenase 4 membrane component.
 
  
 0.973
Rfer_3276
NADH dehydrogenase (quinone).
 
 
 0.913
Rfer_3279
NADH/Ubiquinone/plastoquinone (complex I).
 
 
 0.905
nuoI
NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.725
Your Current Organism:
Rhodoferax ferrireducens
NCBI taxonomy Id: 338969
Other names: Albidiferax ferrireducens T118, R. ferrireducens T118, Rhodoferax ferrireducens ATCC BAA-621, Rhodoferax ferrireducens DSM 15236, Rhodoferax ferrireducens T118, Rhodoferax ferrireducens str. T118, Rhodoferax ferrireducens strain T118
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