| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rfer_3288 | Rfer_4093 | Rfer_3288 | Rfer_4093 | NADH-ubiquinone oxidoreductase, chain 49kDa. | Hydrogenase assembly chaperone hypC/hupF. | 0.595 |
| Rfer_3288 | Rfer_4099 | Rfer_3288 | Rfer_4099 | NADH-ubiquinone oxidoreductase, chain 49kDa. | Hydrogenase expression/formation protein HypD; Belongs to the HypD family. | 0.580 |
| Rfer_3288 | hypA | Rfer_3288 | Rfer_4095 | NADH-ubiquinone oxidoreductase, chain 49kDa. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.779 |
| Rfer_3288 | ureG | Rfer_3288 | Rfer_3408 | NADH-ubiquinone oxidoreductase, chain 49kDa. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.923 |
| Rfer_4093 | Rfer_3288 | Rfer_4093 | Rfer_3288 | Hydrogenase assembly chaperone hypC/hupF. | NADH-ubiquinone oxidoreductase, chain 49kDa. | 0.595 |
| Rfer_4093 | Rfer_4099 | Rfer_4093 | Rfer_4099 | Hydrogenase assembly chaperone hypC/hupF. | Hydrogenase expression/formation protein HypD; Belongs to the HypD family. | 0.992 |
| Rfer_4093 | hypA | Rfer_4093 | Rfer_4095 | Hydrogenase assembly chaperone hypC/hupF. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.903 |
| Rfer_4093 | ureG | Rfer_4093 | Rfer_3408 | Hydrogenase assembly chaperone hypC/hupF. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.608 |
| Rfer_4099 | Rfer_3288 | Rfer_4099 | Rfer_3288 | Hydrogenase expression/formation protein HypD; Belongs to the HypD family. | NADH-ubiquinone oxidoreductase, chain 49kDa. | 0.580 |
| Rfer_4099 | Rfer_4093 | Rfer_4099 | Rfer_4093 | Hydrogenase expression/formation protein HypD; Belongs to the HypD family. | Hydrogenase assembly chaperone hypC/hupF. | 0.992 |
| Rfer_4099 | hypA | Rfer_4099 | Rfer_4095 | Hydrogenase expression/formation protein HypD; Belongs to the HypD family. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.965 |
| Rfer_4099 | ureG | Rfer_4099 | Rfer_3408 | Hydrogenase expression/formation protein HypD; Belongs to the HypD family. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.691 |
| hypA | Rfer_3288 | Rfer_4095 | Rfer_3288 | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | NADH-ubiquinone oxidoreductase, chain 49kDa. | 0.779 |
| hypA | Rfer_4093 | Rfer_4095 | Rfer_4093 | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Hydrogenase assembly chaperone hypC/hupF. | 0.903 |
| hypA | Rfer_4099 | Rfer_4095 | Rfer_4099 | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Hydrogenase expression/formation protein HypD; Belongs to the HypD family. | 0.965 |
| hypA | ureE | Rfer_4095 | Rfer_3406 | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | UreE urease accessory-like; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.426 |
| hypA | ureF | Rfer_4095 | Rfer_3407 | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.426 |
| hypA | ureG | Rfer_4095 | Rfer_3408 | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.712 |
| ureA | ureB | Rfer_3399 | Rfer_3400 | Urease, gamma subunit; Belongs to the urease gamma subunit family. | Urease, beta subunit; Belongs to the urease beta subunit family. | 0.999 |
| ureA | ureC | Rfer_3399 | Rfer_3402 | Urease, gamma subunit; Belongs to the urease gamma subunit family. | Urease, alpha subunit; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. | 0.999 |