Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Rfer_3453Two component, sigma54 specific, transcriptional regulator, Fis family. (445 aa)    
Predicted Functional Partners:
Rfer_3454
Histidine kinase.
 0.994
Rfer_0778
Sigma-54 (RpoN); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.778
Rfer_3574
Periplasmic sensor signal transduction histidine kinase.
 
 
 0.685
Rfer_2981
Signal transduction histidine kinase, nitrogen specific, NtrB.
 
 
 0.642
Rfer_0922
Multi-sensor signal transduction histidine kinase.
 
 
 
 0.636
Rfer_0246
Histidine kinase.
 
 
 0.584
Rfer_3455
Sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
     
 0.578
Rfer_2855
Periplasmic sensor signal transduction histidine kinase.
 
 
 0.559
Rfer_3932
Diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(s).
  
 
 0.554
Rfer_0557
Flagellar motor switch protein FliM.
  
  
 0.530
Your Current Organism:
Rhodoferax ferrireducens
NCBI taxonomy Id: 338969
Other names: Albidiferax ferrireducens T118, R. ferrireducens T118, Rhodoferax ferrireducens ATCC BAA-621, Rhodoferax ferrireducens DSM 15236, Rhodoferax ferrireducens T118, Rhodoferax ferrireducens str. T118, Rhodoferax ferrireducens strain T118
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.