Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rfer_3965Pyruvate dehydrogenase (lipoamide). (356 aa)    
Predicted Functional Partners:
Rfer_3966
Transketolase.
 0.998
Rfer_0386
Transketolase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.995
Rfer_3553
Branched-chain alpha-keto acid dehydrogenase E1 component.
 0.995
Rfer_2504
Transketolase-like.
 0.986
Rfer_2214
Dihydrolipoamide dehydrogenase.
  
 0.941
Rfer_0385
Catalytic domain of components of various dehydrogenase complexes.
 
 0.933
Rfer_3967
Biotin/lipoyl attachment.
 
 0.921
Rfer_3552
Branched-chain alpha-keto acid dehydrogenase E2 component.
 
 0.916
Rfer_2320
2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.887
Rfer_2213
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.827
Your Current Organism:
Rhodoferax ferrireducens
NCBI taxonomy Id: 338969
Other names: Albidiferax ferrireducens T118, R. ferrireducens T118, Rhodoferax ferrireducens ATCC BAA-621, Rhodoferax ferrireducens DSM 15236, Rhodoferax ferrireducens T118, Rhodoferax ferrireducens str. T118, Rhodoferax ferrireducens strain T118
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