| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rfer_1938 | Rfer_3804 | Rfer_1938 | Rfer_3804 | Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Conserved hypothetical protein 701. | 0.933 |
| Rfer_1938 | Rfer_4072 | Rfer_1938 | Rfer_4072 | Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Protoporphyrinogen oxidase. | 0.923 |
| Rfer_1938 | hemF | Rfer_1938 | Rfer_2077 | Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.940 |
| Rfer_1938 | hemH | Rfer_1938 | Rfer_1545 | Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.546 |
| Rfer_3804 | Rfer_1938 | Rfer_3804 | Rfer_1938 | Conserved hypothetical protein 701. | Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.933 |
| Rfer_3804 | Rfer_4072 | Rfer_3804 | Rfer_4072 | Conserved hypothetical protein 701. | Protoporphyrinogen oxidase. | 0.900 |
| Rfer_3804 | hemF | Rfer_3804 | Rfer_2077 | Conserved hypothetical protein 701. | Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.943 |
| Rfer_3804 | hemH | Rfer_3804 | Rfer_1545 | Conserved hypothetical protein 701. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.944 |
| Rfer_4071 | Rfer_4072 | Rfer_4071 | Rfer_4072 | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. | Protoporphyrinogen oxidase. | 0.441 |
| Rfer_4072 | Rfer_1938 | Rfer_4072 | Rfer_1938 | Protoporphyrinogen oxidase. | Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.923 |
| Rfer_4072 | Rfer_3804 | Rfer_4072 | Rfer_3804 | Protoporphyrinogen oxidase. | Conserved hypothetical protein 701. | 0.900 |
| Rfer_4072 | Rfer_4071 | Rfer_4072 | Rfer_4071 | Protoporphyrinogen oxidase. | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. | 0.441 |
| Rfer_4072 | hemF | Rfer_4072 | Rfer_2077 | Protoporphyrinogen oxidase. | Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.926 |
| Rfer_4072 | hemH | Rfer_4072 | Rfer_1545 | Protoporphyrinogen oxidase. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.928 |
| hemF | Rfer_1938 | Rfer_2077 | Rfer_1938 | Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.940 |
| hemF | Rfer_3804 | Rfer_2077 | Rfer_3804 | Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Conserved hypothetical protein 701. | 0.943 |
| hemF | Rfer_4072 | Rfer_2077 | Rfer_4072 | Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Protoporphyrinogen oxidase. | 0.926 |
| hemF | hemH | Rfer_2077 | Rfer_1545 | Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.709 |
| hemH | Rfer_1938 | Rfer_1545 | Rfer_1938 | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.546 |
| hemH | Rfer_3804 | Rfer_1545 | Rfer_3804 | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Conserved hypothetical protein 701. | 0.944 |