Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Rfer_4094Conserved hypothetical protein. (165 aa)    
Predicted Functional Partners:
Rfer_4092
HybD peptidase. Aspartic peptidase. MEROPS family A31.
 
  
 0.957
Rfer_4088
Hydrogenase (NiFe) small subunit (hydA).
 
 
 0.943
Rfer_4091
Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.935
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.934
Rfer_4096
Hydrogenase accessory protein HypB.
 
  
 0.884
Rfer_4120
Uptake hydrogenase accessory protein HupU.
 
 
 0.873
Rfer_4099
Hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
  
 0.848
Rfer_4118
Putative hydrogenase expression/formation protein HupK.
 
  
 0.840
Rfer_4121
Hydrogen:quinone oxidoreductase.
 
  
 0.829
Rfer_4100
Hydrogenase expression/formation protein HypE.
 
   
 0.826
Your Current Organism:
Rhodoferax ferrireducens
NCBI taxonomy Id: 338969
Other names: Albidiferax ferrireducens T118, R. ferrireducens T118, Rhodoferax ferrireducens ATCC BAA-621, Rhodoferax ferrireducens DSM 15236, Rhodoferax ferrireducens T118, Rhodoferax ferrireducens str. T118, Rhodoferax ferrireducens strain T118
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