STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpmEUnannotated protein; Binds the 23S rRNA. (73 aa)    
Predicted Functional Partners:
rplY
Unannotated protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
  
 
 0.999
rplU
Unannotated protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
 
 
 0.999
rpmA
Unannotated protein; Belongs to the bacterial ribosomal protein bL27 family.
 
 
 0.999
rpsT
Unannotated protein; Binds directly to 16S ribosomal RNA.
  
 
 0.999
rpmB-2
Unannotated protein; Belongs to the bacterial ribosomal protein bL28 family.
 
 
 0.999
rpsP
Unannotated protein; Belongs to the bacterial ribosomal protein bS16 family.
  
 
 0.999
rplS
Unannotated protein; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
 
 0.999
rpmG-2
Unannotated protein; Belongs to the bacterial ribosomal protein bL33 family.
  
 
 0.999
rpsL
Unannotated protein; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
 
 0.999
rpsG
Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
 
 0.999
Your Current Organism:
Streptomyces galbus
NCBI taxonomy Id: 33898
Other names: ATCC 23910, BCRC 12166, CBS 831.68, CCRC 12166, CCRC:12166, DSM 40089, IFO 12864, IMET 42937, ISP 5089, JCM 4222, JCM 4639, NBRC 12864, NCIMB 13005, NRRL B-2283, NRRL-ISP 5089, S. galbus, VKM Ac-165
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.