STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCA_000772895_04828Unannotated protein. (996 aa)    
Predicted Functional Partners:
sbcD
Unannotated protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 0.999
GCA_000772895_06214
Unannotated protein.
 
 0.998
E4U92_01635
Unannotated protein.
  
 0.991
polA
Unannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.977
E4U92_22095
Unannotated protein.
  
 0.947
E4U92_07910
Unannotated protein.
  
 0.931
recQ
Unannotated protein.
  
 0.931
recA
Unannotated protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.879
GCA_000772895_06603
Unannotated protein.
  
 0.870
arc
Unannotated protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
 
 0.867
Your Current Organism:
Streptomyces galbus
NCBI taxonomy Id: 33898
Other names: ATCC 23910, BCRC 12166, CBS 831.68, CCRC 12166, CCRC:12166, DSM 40089, IFO 12864, IMET 42937, ISP 5089, JCM 4222, JCM 4639, NBRC 12864, NCIMB 13005, NRRL B-2283, NRRL-ISP 5089, S. galbus, VKM Ac-165
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.