STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pkn4Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (754 aa)    
Predicted Functional Partners:
KUN56633.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.915
PrpH
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.880
PrpB8
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.848
KUN53802.1
Phosphatidylinositol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.831
alaS
alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 0.817
OsaA
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.716
KUN53226.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.711
KUN55295.1
FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.708
KUN54054.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.702
FabG8
beta-ketoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.698
Your Current Organism:
Streptomyces avermitilis
NCBI taxonomy Id: 33903
Other names: ATCC 31267, DSM 46492, JCM 5070, NBRC 14893, NCIMB 12804, NRRL 8165, S. avermitilis, Streptomyces avermectinius, Streptomyces avermectinius Takahashi et al. 2002, strain MA-4680
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