STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PrpM4Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (690 aa)    
Predicted Functional Partners:
OsaA
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.898
KUN52316.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.858
rsbV_2
Anti-sigma B factor antagonist; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.837
MutM2
DNA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPG family.
       0.807
arsI
Metal ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.765
PrpB6
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.749
rsbV_4
Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.745
PrpB1
Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.744
PrpB12
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.735
KUN51496.1
Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.734
Your Current Organism:
Streptomyces avermitilis
NCBI taxonomy Id: 33903
Other names: ATCC 31267, DSM 46492, JCM 5070, NBRC 14893, NCIMB 12804, NRRL 8165, S. avermitilis, Streptomyces avermectinius, Streptomyces avermectinius Takahashi et al. 2002, strain MA-4680
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.