node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HypC | hypA | AQJ43_17855 | AQJ43_17870 | Ni/Fe hydrogenase formation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.968 |
HypC | ureG | AQJ43_17855 | AQJ43_19220 | Ni/Fe hydrogenase formation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.735 |
hypA | HypC | AQJ43_17870 | AQJ43_17855 | Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Ni/Fe hydrogenase formation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.968 |
hypA | ureAB | AQJ43_17870 | AQJ43_27825 | Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Urease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the urease beta subunit family. | 0.522 |
hypA | ureG | AQJ43_17870 | AQJ43_19220 | Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.853 |
tsaD | ureG | AQJ43_22905 | AQJ43_19220 | tRNA threonylcarbamoyl adenosine modification protein TsaD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.756 |
ureA | ureAB | AQJ43_19240 | AQJ43_27825 | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | Urease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the urease beta subunit family. | 0.996 |
ureA | ureB | AQJ43_19240 | AQJ43_19235 | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | Urease subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease beta subunit family. | 0.999 |
ureA | ureC | AQJ43_19240 | AQJ43_19230 | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
ureA | ureC2 | AQJ43_19240 | AQJ43_27830 | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | Urease subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
ureA | ureD | AQJ43_19240 | AQJ43_19215 | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | Urease accessory protein ureD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.970 |
ureA | ureF | AQJ43_19240 | AQJ43_19225 | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.986 |
ureA | ureG | AQJ43_19240 | AQJ43_19220 | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.985 |
ureAB | hypA | AQJ43_27825 | AQJ43_17870 | Urease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the urease beta subunit family. | Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.522 |
ureAB | ureA | AQJ43_27825 | AQJ43_19240 | Urease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the urease beta subunit family. | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | 0.996 |
ureAB | ureB | AQJ43_27825 | AQJ43_19235 | Urease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the urease beta subunit family. | Urease subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease beta subunit family. | 0.996 |
ureAB | ureC | AQJ43_27825 | AQJ43_19230 | Urease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the urease beta subunit family. | Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
ureAB | ureC2 | AQJ43_27825 | AQJ43_27830 | Urease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the urease beta subunit family. | Urease subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
ureAB | ureD | AQJ43_27825 | AQJ43_19215 | Urease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the urease beta subunit family. | Urease accessory protein ureD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.965 |
ureAB | ureF | AQJ43_27825 | AQJ43_19225 | Urease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the urease beta subunit family. | Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.979 |