STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTHE_0022Haloacid dehalogenase-like hydrolase (HAD superfamily). (227 aa)    
Predicted Functional Partners:
BTHE_0906
tRNA (adenine-N(1)-)-methyltransferase.
      0.833
BTHE_0043
Haloacid dehalogenase-like hydrolase (HAD superfamily).
  
     0.768
BTHE_0394
Glucose-specific II BC.
  
  
 0.589
BTHE_1798
DnaJ-class molecular chaperone.
   
   0.558
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
   0.558
BTHE_1797
MerR HTH family regulatory protein.
       0.506
grpE
Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]
       0.506
BTHE_0021
Hypothetical protein.
  
    0.479
BTHE_1051
Amylopullulanase.
 
  
 0.465
BTHE_1795
DedA integral membrane protein.
  
    0.440
Your Current Organism:
Bifidobacterium thermophilum
NCBI taxonomy Id: 33905
Other names: AS 1.2235, ATCC 25525, B. thermophilum, BCRC 14669, Bifidobacterium ruminale, Bifidobacterium thermophilium, CCRC 14669, CCRC:14669, CCUG 34983, CIP 105420, DSM 20210, HAMBI 111, LMG 11573, LMG:11573
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