STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTHE_05153-deoxy-7-phosphoheptulonate synthase, Phe-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (378 aa)    
Predicted Functional Partners:
aroK
Shikimate kinase/3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
  
 
 0.745
BTHE_0514
3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase.
 
    
0.738
BTHE_0516
PepC2 Aminopeptidase C; Belongs to the peptidase C1 family.
       0.728
BTHE_0513
Pfs 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
  
    0.673
BTHE_0517
Hypothetical protein.
       0.634
BTHE_0518
Pcp Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
     
 0.595
BTHE_0677
Prephenate dehydrogenase.
  
  
 0.501
BTHE_0510
Two-component response regulator.
     
 0.475
BTHE_0511
Histidine kinase sensor of two-component system protein.
     
 0.416
BTHE_0679
pheA Prephenate dehydratase.
  
  
 0.409
Your Current Organism:
Bifidobacterium thermophilum
NCBI taxonomy Id: 33905
Other names: AS 1.2235, ATCC 25525, B. thermophilum, BCRC 14669, Bifidobacterium ruminale, Bifidobacterium thermophilium, CCRC 14669, CCRC:14669, CCUG 34983, CIP 105420, DSM 20210, HAMBI 111, LMG 11573, LMG:11573
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