STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTHE_1140Mn2+-Zn2+ transporter of ABC trasporter system, permease MntA. (323 aa)    
Predicted Functional Partners:
BTHE_1141
Mn2+-Zn2+ transporter of ABC trasporter system, ATP-binding protein MntB.
 
 
 0.997
BTHE_1137
Mn2+-Zn2+ transporter of ABC trasporter system, binding protein MntC.
 
  
 0.969
BTHE_0208
Solute binding protein of ABC transporter system.
 
  
 0.914
folD
Bifunctional methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.672
BTHE_1968
ABC transporter ATP-binding protein.
 
     0.669
BTHE_0096
ABC superfamily ATP binding cassette transporter ABC protein.
 
  
 0.618
RpsA
30S ribosomal protein S1.
       0.612
BTHE_0209
Ferric uptake regulation protein; Belongs to the Fur family.
  
  
 0.592
BTHE_1134
dephospho-CoA kinase.
       0.589
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.573
Your Current Organism:
Bifidobacterium thermophilum
NCBI taxonomy Id: 33905
Other names: AS 1.2235, ATCC 25525, B. thermophilum, BCRC 14669, Bifidobacterium ruminale, Bifidobacterium thermophilium, CCRC 14669, CCRC:14669, CCUG 34983, CIP 105420, DSM 20210, HAMBI 111, LMG 11573, LMG:11573
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